GM attributed the change of strategy to “the considerable time and resources that would be needed to scale the business”.
The company did not say how many Cruise employees could be moved over to GM.
GM, which owns about 90% of Cruise, said it has agreements with other shareholders that will raise its ownership to more than 97%.
In December 2023, Cruise said it would cut 900 jobs, about a quarter of its workforce.
Cruise had earlier pulled all of its US vehicles from testing after California halted its driverless testing permit.
In October 2023, one of its vehicles hit a pedestrian and dragged her for more than 20ft (6m), leaving her seriously injured.
Cruise admitted, external to submitting a false report to the National Highway Traffic Safety Administration in connection to that crash, resolving a criminal investigation last month.
Federal prosecutors said Cruise employees did not include a description of the pedestrian being dragged as part of their account on the morning after the incident.
Cruise co-founder Kyle Vogt left the company a few weeks later.
On Tuesday, following GM’s announcement, Mr Vogt posted on the social media platform X, external “In case it was unclear before, it is clear now: GM are a bunch of dummies.”
The Detroit-based manufacturer’s chief executive Mary Barra has previously predicted that the Cruise business could generate $50bn (£39bn) in annual revenue by 2030.
Rival motor manufacturing firms have also struggled with projects to build autonomous vehicles.
In 2022, Ford and Volkswagen announced that they would shut down Argo AI, their self-driving car joint venture.
Meanwhile, the emerging robotaxi industry has long attracted major players.
As well as Tesla, competitors to create self-driving cabs include Waymo, a subsidiary of Google’s parent company Alphabet – and technology giant Amazon.
